Article
Quantitative trait Loci for resistance to the congenital nephropathy in tensin 2-deficient mice.
PloS one - 1 Jan 2014
Sasaki Hayato, Sasaki Nobuya, Nishino Tomohiro, Nagasaki Ken-Ichi, Kitamura Hiroshi, Torigoe Daisuke, Agui Takashi
Abstract excerpt
The ICR-derived glomerulonephritis (ICGN) mouse is a chronic kidney disease (CKD) model that is characterized histologically by glomerulosclerosis, vascular sclerosis and tubulointerstitial fibrosis, and clinically by proteinuria and anemia, which are common symptoms and pathological changes associated with a variety of kidney diseases. Previously, we performed a quantitative trait locus (QTL) analysis to...
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