Article
Proteinuria-induced chronic kidney disease in the ICGN/Oa mice with a mutation of Tensin2 gene.
Renal failure - 1 Jan 2009
Kato Takashi, Kurosawa Tsutomu Miki, Taketo Makoto Mark
Abstract excerpt
ICGN/Oa mice are used to study the pathophysiological mechanisms underlying proteinuria-induced chronic kidney disease (CKD). Recently, a mutation of tensin2 gene (Tns2) was suggested to be responsible for proteinuria in the inbred ICGN mice. We identified the wild-type (+/+), heterozygous (+/nep...
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