Article

A Bigenic mouse model of FSGS reveals perturbed pathways in podocytes, mesangial cells and endothelial cells

2019-04-18

Abstract excerpt

Focal segmental glomerulosclerosis is a major cause of end stage renal disease. Many patients prove unresponsive to available therapies. An improved understanding of the molecular basis of the disease process could provide insights leading to novel therapeutic approaches. In this study we carried out an RNA-seq analysis of the altered gene expression patterns of podocytes, mesangial cells and glomerular endothelia...

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Literature Corpus work: dcca9f4c-5bfd-5e68-ab63-fa4416f8b75a
DOI: 10.1101/613679

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