Article
Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese.
Nature communications - 31 May 2016
Li Yuanfeng, Si Lanlan, Zhai Yun, Hu Yanling, Hu Zhibin, Bei Jin-Xin, Xie Bobo, Ren Qian, Cao Pengbo, Yang Fei, Song Qingfeng, Bao Zhiyu, Zhang Haitao, Han Yuqing, Wang Zhifu, Chen Xi, Xia Xia, Yan Hongbo, Wang Rui, Zhang Ying, Gao Chengming, Meng Jinfeng, Tu Xinyi, Liang Xinqiang, Cui Ying, Liu Ying, Wu Xiaopan, Li Zhuo, Wang Huifen, Li Zhaoxia, Hu Bo, He Minghui, Gao Zhibo, Xu Xiaobing, Ji Hongzan, Yu Chaohui, Sun Yi, Xing Baocai, Yang Xiaobo, Zhang Haiying, Tan Aihua, Wu Chunlei, Jia Weihua, Li Shengping, Zeng Yi-Xin, Shen Hongbing, He Fuchu, Mo Zengnan, Zhang Hongxing, Zhou Gangqiao
Abstract excerpt
Hepatitis B virus (HBV) infection is a common infectious disease. Here we perform a genome-wide association study (GWAS) among Chinese populations to identify novel genetic loci involved in persistent HBV infection. GWAS scan is performed in 1,251 persistently HBV infected subjects (PIs, cases) and 1,057 spontaneously recovered subjects (SRs, controls), followed by replications in four independent populations...
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