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Association study of IFNAR2 and IL10RB genes with the susceptibility and interferon response in HBV infection

13 Aug 2009

Abstract excerpt

A recent genome-wide association study discovered that two polymorphisms, interferon (IFN) alpha receptor 2 (IFNAR-2) F8S and interleukin 10 receptor (IL10RB) K47E, were associated with susceptibility to hepatitis B virus (HBV) infection in Africa. Here, we reevaluate the effects of the two polymorphisms on HBV susceptibility in the Chinese Han population, and extended the study to look at their association with...

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PMID: 19714778
DOI: 10.1111/j.1365-2893.2009.01130.x

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