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Article

Persistent effect of IFNAR-1 genetic polymorphism on the long-term pathogenesis of chronic HBV infection.

Viral immunology - 1 Jun 2010

He Xing-Xing, Chang Ying, Jiang Hua-Jun, Tang Feng, Meng Fan-Ying, Xie Qiong-Hui, Li Pei-Yuan, Song Yu-Hu, Lin Ju-Sheng

Abstract excerpt

Genetic polymorphism of IFNAR-1 plays a large role in determining the clearance or chronicity after hepatitis B virus (HBV) exposure. However, it is not clear whether type I interferon receptor-1 (IFNAR-1) variations continuously exert their effects to influence the final outcomes following HBV chronicity, including acute-on-chronic hepatitis B liver failure (ACLF-HBV), chronic hepatitis B (CHB), liver cirrhosis...

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Source

Identifiers

PMID: 20565290
DOI: 10.1089/vim.2009.0102

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Source receipt: pubmed, retrieved 7 Sept 2026.

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