Article
Transcriptome-wide association study for persistent hepatitis B virus infection and related hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver - 1 Sept 2020
Han Jing, Chen Congcong, Wang Cheng, Qin Na, Huang Mingtao, Ma Zijian, Zhu Meng, Dai Juncheng, Jiang Yue, Ma Hongxia, Jin Guangfu, Shen Hongbing, Hu Zhibin
Abstract excerpt
BACKGROUND & AIMS: Previous genome-wide association studies (GWAS) have identified multiple susceptible variants associated with persistent hepatitis B virus (HBV) infection. However, most of these variants are located in the noncoding regions, which make it difficult to determine the effective genes underlying these associations. We performed a two-stage study, in the first stage we integrated RNA sequencing...
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