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Article

Distinctive Drug-resistant Mutation Profiles and Interpretations of HIV-1 Proviral DNA Revealed by Deep Sequencing in Reverse Transcriptase.

Biomedical and environmental sciences : BES - 1 Apr 2016

Yin Qian Qian, Li Zhen Peng, Zhao Hai, Pan Dong, Wang Yan, Xu Wei Si, Xing Hui, Feng Yi, Jiang Shi Bo, Shao Yi Ming, Ma Li Ying

Abstract excerpt

OBJECTIVE: To investigate distinctive features in drug-resistant mutations (DRMs) and interpretations for reverse transcriptase inhibitors (RTIs) between proviral DNA and paired viral RNA in HIV-1-infected patients. METHODS: Forty-three HIV-1-infected individuals receiving first-line antiretrovir...

Topics

Adult
Antiviral Agents
China
DNA, Viral
Drug Resistance, Viral
Female
HIV Infections
HIV-1
High-Throughput Nucleotide Sequencing
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Proviruses

RNA, Viral

RNA-Directed DNA Polymerase

Source

Identifiers

PMID: 27241734
DOI: 10.3967/bes2016.031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-27241734-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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