Article
Distinctive Drug-resistant Mutation Profiles and Interpretations of HIV-1 Proviral DNA Revealed by Deep Sequencing in Reverse Transcriptase.
Biomedical and environmental sciences : BES - 1 Apr 2016
Yin Qian Qian, Li Zhen Peng, Zhao Hai, Pan Dong, Wang Yan, Xu Wei Si, Xing Hui, Feng Yi, Jiang Shi Bo, Shao Yi Ming, Ma Li Ying
Abstract excerpt
OBJECTIVE: To investigate distinctive features in drug-resistant mutations (DRMs) and interpretations for reverse transcriptase inhibitors (RTIs) between proviral DNA and paired viral RNA in HIV-1-infected patients. METHODS: Forty-three HIV-1-infected individuals receiving first-line antiretroviral therapy were recruited to participate in a multicenter AIDS Cohort Study in Anhui and Henan Provinces in China in...
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