Article
HIV-1 proviral resistance mutations: usefulness in clinical practice.
HIV medicine - 1 Sept 2010
Kabamba-Mukadi B, Duquenne A, Henrivaux P, Musuamba F, Ruelle J, Yombi J-C, Bodéus M, Vandercam B, Goubau P
Abstract excerpt
OBJECTIVES: Transmitted HIV strains may harbour drug resistance mutations. HIV-1 drug resistance mutations are currently detected in plasma viral RNA. HIV-1 proviral DNA could be an alternative marker, as it persists in infected cells. METHODS: This was a prospective study assessing the prevalence and persistence of HIV-1 drug resistance mutations in DNA from CD4 cells before and after protease inhibitor (PI)- or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
