HIV-1 proviral resistance mutations: usefulness in clinical practice.

doi:10.1111/j.1468-1293.2009.00814.x

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Article

HIV-1 proviral resistance mutations: usefulness in clinical practice.

HIV medicine - 1 Sept 2010

Kabamba-Mukadi B, Duquenne A, Henrivaux P, Musuamba F, Ruelle J, Yombi J-C, Bodéus M, Vandercam B, Goubau P

Abstract excerpt

OBJECTIVES: Transmitted HIV strains may harbour drug resistance mutations. HIV-1 drug resistance mutations are currently detected in plasma viral RNA. HIV-1 proviral DNA could be an alternative marker, as it persists in infected cells. METHODS: This was a prospective study assessing the prevalence and persistence of HIV-1 drug resistance mutations in DNA from CD4 cells before and after protease inhibitor (PI)- or...

Topics

Adult
Aged
Amino Acid Sequence
Anti-Retroviral Agents
CD4 Lymphocyte Count
CD4-Positive T-Lymphocytes
DNA Mutational Analysis
DNA, Viral
Drug Resistance, Viral
Drug Therapy, Combination
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

HIV Infections

HIV-1

Humans

Logistic Models

Male

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 20163482
DOI: 10.1111/j.1468-1293.2009.00814.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20163482-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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