Article
HIV drug resistance mutations in proviral DNA from a community treatment program.
PloS one - 1 Jan 2015
Derache Anne, Shin Hyoung-Shik, Balamane Maya, White Elizabeth, Israelski Dennis, Klausner Jeffrey D, Freeman Alexandra H, Katzenstein David
Abstract excerpt
BACKGROUND: Drug resistance mutations archived in resting memory CD4+ cells may persist despite suppression of HIV RNA to <50 copies/ml. We sequenced pol gene from proviral DNA among viremic and suppressed patients to identify drug resistance mutations. METHODS: The Peninsula AIDS Research Cohort study enrolled and followed over 2 years 120 HIV infected patients from San Mateo and San Francisco Counties. HIV-1...
Topics
- Adult
- Antiretroviral Therapy, Highly Active
- DNA, Viral
- Demography
- Drug Resistance, Viral
- Female
- Follow-Up Studies
- HIV Infections
- HIV-1
- Humans
- Male