Article
Gene-based analysis identified the gene ZNF248 is associated with late-onset asthma in African Americans.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Jul 2016
Wang Leyao, Salinas Yasmmyn D, DeWan Andrew T
Abstract excerpt
BACKGROUND: Late-onset asthma (LOA) has distinct characteristics and its pathogenesis might rely on unique pathways. Although current studies are focused primarily on childhood asthma, more research is needed to show the mechanisms underlying LOA. OBJECTIVE: To conduct genomewide association analysis and gene-based analysis to identify single-nucleotide polymorphisms and genes associated with LOA. METHODS: The...
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