Identification of Four Novel Loci in Asthma in European American and African American Populations.

doi:10.1164/rccm.201604-0861OC

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Article

Identification of Four Novel Loci in Asthma in European American and African American Populations.

American journal of respiratory and critical care medicine - 15 Feb 2017

Almoguera Berta, Vazquez Lyam, Mentch Frank, Connolly John, Pacheco Jennifer A, Sundaresan Agnes S, Peissig Peggy L, Linneman James G, McCarty Catherine A, Crosslin David, Carrell David S, Lingren Todd, Namjou-Khales Bahram, Harley John B, Larson Eric, Jarvik Gail P, Brilliant Murray, Williams Marc S, Kullo Iftikhar J, Hysinger Erik B, Sleiman Patrick M A, Hakonarson Hakon

Abstract excerpt

RATIONALE: Despite significant advances in knowledge of the genetic architecture of asthma, specific contributors to the variability in the burden between populations remain uncovered. OBJECTIVES: To identify additional genetic susceptibility factors of asthma in European American and African American populations. METHODS: A phenotyping algorithm mining electronic medical records was developed and validated to...

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PMID: 27611488
DOI: 10.1164/rccm.201604-0861OC
PMCID: PMC5378422

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