Article
Identification of ATPAF1 as a novel candidate gene for asthma in children.
The Journal of allergy and clinical immunology - 1 Oct 2011
Schauberger Eric M, Ewart Susan L, Arshad Syed H, Huebner Marianne, Karmaus Wilfried, Holloway John W, Friderici Karen H, Ziegler Julie T, Zhang Hongmei, Rose-Zerilli Matthew J, Barton Sheila J, Holgate Stephen T, Kilpatrick Jeffrey R, Harley John B, Lajoie-Kadoch Stephane, Harley Isaac T W, Hamid Qutayba, Kurukulaaratchy Ramesh J, Seibold Max A, Avila Pedro C, Rodriguez-Cintrón William, Rodriguez-Santana Jose R, Hu Donglei, Gignoux Christopher, Romieu Isabelle, London Stephanie J, Burchard Esteban G, Langefeld Carl D, Wills-Karp Marsha
Abstract excerpt
BACKGROUND: Asthma is a common disease of children with a complex genetic origin. Understanding the genetic basis of asthma susceptibility will allow disease prediction and risk stratification. OBJECTIVE: We sought to identify asthma susceptibility genes in children. METHODS: A nested case-control genetic association study of children of Caucasian European ancestry from a birth cohort was conducted. Single...
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