Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma

21 Jun 2023

Abstract excerpt

Introduction: Asthma is a chronic disease of the airways that impairs normal breathing. The etiology of asthma is complex and involves multiple factors, including the environment and genetics, especially the distinct genetic architecture associated with ancestry. Compared to early-onset asthma, little is known about genetic predisposition to late-onset asthma. We investigated the race/ethnicity-specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to IL-33, ST2, and ILC Pathways
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37415598
DOI: 10.3389/fgene.2023.1173676

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthmaPMID 37415598Read ↗

Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region.Semantic proximity Read ↗

Advances in asthma and allergic disease genetics: Is bigger always better?Semantic proximity Read ↗

Discerning asthma endotypes through comorbidity mapping.Semantic proximity Read ↗

Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversitySemantic proximity Read ↗

Novel Genetic Risk factors for Asthma in African American Children: Precision Medicine and The SAGE II StudySemantic proximity Read ↗

Shared and Distinct Genetic Risk Factors for Childhood Onset and Adult Onset Asthma: Genome- and Transcriptome-wide StudiesSemantic proximity Read ↗

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.Semantic proximity Read ↗

Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.Semantic proximity Read ↗

Multi-trait genetic analysis of asthma and eosinophils uncovers pleiotropic loci in East AsiansSemantic proximity Read ↗

An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.Semantic proximity Read ↗

Novel genetic risk factors for asthma in African American children: Precision Medicine and the SAGE II Study.Semantic proximity Read ↗

Multi-ancestry fine-mapping of the chromosome 17q12-q21 asthma locus identifies independent associations implicating lymphocyte and eosinophil levels in the causal pathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.