Article
Haplotype and diplotype analyses of variation in ERCC5 transcription cis-regulation in normal bronchial epithelial cells.
Physiological genomics - 1 Jul 2016
Zhang Xiaolu, Crawford Erin L, Blomquist Thomas M, Khuder Sadik A, Yeo Jiyoun, Levin Albert M, Willey James C
Abstract excerpt
Excision repair cross-complementation group 5 (ERCC5) gene plays an important role in nucleotide excision repair, and dysregulation of ERCC5 is associated with increased lung cancer risk. Haplotype and diplotype analyses were conducted in normal bronchial epithelial cells (NBEC) to better understand mechanisms responsible for interindividual variation in transcript abundance regulation of ERCC5 We determined...
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