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Article

Association studies of excision repair cross-complementation group 1 (ERCC1) haplotypes with lung and head and neck cancer risk in a Caucasian population.

Cancer epidemiology - 1 Apr 2011

Jones Nathan R, Spratt Thomas E, Berg Arthur S, Muscat Joshua E, Lazarus Philip, Gallagher Carla J

Abstract excerpt

BACKGROUND: The formation of bulky DNA adducts caused by diol epoxide derivatives of polycyclic aromatic hydrocarbons has been associated with tobacco-induced cancers, and inefficient repair of such adducts by the nucleotide excision repair (NER) system has been linked to increased risk of tobacco-induced lung and head and neck (H&N) cancers. The human excision repair cross-complementation group 1 (ERCC1) protein...

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Source

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Identifiers

PMID: 20863778
DOI: 10.1016/j.canep.2010.08.007
PMCID: PMC3081042

Genes

ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association studies of excision repair cross-complementation group 1 (ERCC1) haplotypes with lung and head and neck cancer risk in a Caucasian population.PMID 20863778Read ↗

HapMap-based study of the DNA repair gene ERCC2 and lung cancer susceptibility in a Chinese population.Semantic proximity Read ↗

Characterization of functional excision repair cross-complementation group 1 variants and their association with lung cancer risk and prognosis.Semantic proximity Read ↗

Tagging single nucleotide polymorphisms in excision repair cross-complementing group 1 (ERCC1) and risk of primary lung cancer in a Chinese population.Semantic proximity Read ↗

ERCC2, ERCC1 polymorphisms and haplotypes, cooking oil fume and lung adenocarcinoma risk in Chinese non-smoking females.Semantic proximity Read ↗

HapMap-based study of a region encompassing ERCC1 and ERCC2 related to lung cancer susceptibility in a Chinese population.Semantic proximity Read ↗

Variants in DNA double-strand break repair and DNA damage-response genes and susceptibility to lung and head and neck cancers.Semantic proximity Read ↗

Polymorphisms in excision repair cross-complementing group 4 (ERCC4) and susceptibility to primary lung cancer in a Chinese Han population.Semantic proximity Read ↗

Excision repair cross complementation group 1 polymorphisms and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

Genotypes and haplotypes of ERCC1 and ERCC2/XPD genes predict levels of benzo[a]pyrene diol epoxide-induced DNA adducts in cultured primary lymphocytes from healthy individuals: a genotype-phenotype correlation analysis.Semantic proximity Read ↗

Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

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Association studies of ERCC1 polymorphisms with lung cancer susceptibility: a systematic review and meta-analysis.Semantic proximity Read ↗

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