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Article

Inter-individual variation in nucleotide excision repair pathway is modulated by non-synonymous polymorphisms in ERCC4 and MBD4 genes.

Mutation research - 1 Jan 2000

Allione Alessandra, Guarrera Simonetta, Russo Alessia, Ricceri Fulvio, Purohit Rituraj, Pagnani Andrea, Rosa Fabio, Polidoro Silvia, Voglino Floriana, Matullo Giuseppe

Abstract excerpt

Inter-individual differences in DNA repair capacity (DRC) may lead to genome instability and, consequently, modulate individual cancer risk. Among the different DNA repair pathways, nucleotide excision repair (NER) is one of the most versatile, as it can eliminate a wide range of helix-distorting DNA lesions caused by ultraviolet light irradiation and chemical mutagens. We performed a genotype-phenotype...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24004570
DOI: 10.1016/j.mrfmmm.2013.08.005

Genes

ERCC4
MBD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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