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Article

Single nucleotide polymorphisms 5' upstream the coding region of the NEIL2 gene influence gene transcription levels and alter levels of genetic damage.

Genes, chromosomes & cancer - 1 Nov 2008

Kinslow Carla J, El-Zein Randa A, Hill Courtney E, Wickliffe Jeffrey K, Abdel-Rahman Sherif Z

Abstract excerpt

NEIL2 (EC 4.2.99.18), a mammalian DNA glycosylase and ortholog of the bacterial Fpg/Nei, excises oxidized DNA lesions from bubble or single-stranded structures, suggesting its involvement in transcription-coupled DNA repair. Because base excision repair (BER) proteins act collectively and in a progressive fashion, their proper balance is essential for optimal repair. Thus, inter-individual variability in...

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Source

Identifiers

PMID: 18651651
DOI: 10.1002/gcc.20594

Genes

NEIL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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