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Polymorphisms of XPG/ERCC5 and risk of squamous cell carcinoma of the head and neck

1 Dec 2011

Abstract excerpt

OBJECTIVES: Xeroderma pigmentosum group G (XPG) protein is essential for the nucleotide excision repair system, and genetic variations in XPG/ERCC5 that affect DNA repair capacity may contribute to the risk of tobacco-induced cancers, including squamous cell carcinoma of the head and neck (SCCHN). We investigated the association between XPG/ERCC5 polymorphisms and risk of SCCHN. METHODS: We genotyped 12 tagging...

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PMID: 22108238
DOI: 10.1097/fpc.0b013e32834e3cf6

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