Article
Concordant gene expression in leukemia cells and normal leukocytes is associated with germline cis-SNPs.
PloS one - 14 May 2008
French Deborah, Yang Wenjian, Hamilton Leo H, Neale Geoffrey, Fan Yiping, Downing James R, Cox Nancy J, Pui Ching-Hon, Evans William E, Relling Mary V
Abstract excerpt
The degree to which gene expression covaries between different primary tissues within an individual is not well defined. We hypothesized that expression that is concordant across tissues is more likely influenced by genetic variability than gene expression which is discordant between tissues. We quantified expression of 11,873 genes in paired samples of primary leukemia cells and normal leukocytes from 92...
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