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Article

Interethnic variability of ERCC2 polymorphisms.

The pharmacogenomics journal - 1 Jan 2005

King C R, Yu J, Freimuth R R, McLeod H L, Marsh S

Abstract excerpt

Excision Repair Cross-Complementing Rodent Repair Group 2 (ERCC2) plays an important role in DNA repair by eliminating bulky DNA adducts produced by platinum agents during the nucleotide excision repair pathway. Several studies have associated polymorphisms in ERCC2 with response to platinum therapy, lung cancer risk, and DNA repair capacity. This study examined ERCC2 polymorphisms and haplotype structure across...

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Identifiers

PMID: 15534626
DOI: 10.1038/sj.tpj.6500283

Genes

ERCC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interethnic variability of ERCC2 polymorphisms.PMID 15534626Read ↗

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ERCC1 single nucleotide polymorphism C8092A, but not its expression is associated with survival of esophageal squamous cell carcinoma patients from Fujian province, China.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in ERCC2 gene and their haplotypes with esophageal squamous cell carcinoma.Semantic proximity Read ↗

Meta-analysis of two ERCC2 (XPD) polymorphisms, Asp312Asn and Lys751Gln, in breast cancer.Semantic proximity Read ↗

XRCC3 and XPD/ERCC2 single nucleotide polymorphisms and the risk of cancer: a HuGE review.Semantic proximity Read ↗

Association studies of excision repair cross-complementation group 1 (ERCC1) haplotypes with lung and head and neck cancer risk in a Caucasian population.Semantic proximity Read ↗

Nucleotide excision repair gene ERCC1 polymorphisms contribute to cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

Frequency distribution of DNA repair genes ERCC1 and ERCC2 polymorphisms in South Indian healthy population.Semantic proximity Read ↗

Effect of ERCC1 polymorphisms on the response to platinum-based chemotherapy: A systematic review and meta-analysis based on Asian population.Semantic proximity Read ↗

Association between polymorphisms in ERCC2 gene and oral cancer risk: evidence from a meta-analysis.Semantic proximity Read ↗

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