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Article

Antagonistic control of the turnover pathway for the global regulatory sRNA CsrB by the CsrA and CsrD proteins.

Nucleic acids research - 19 Sept 2016

Vakulskas Christopher A, Leng Yuanyuan, Abe Hazuki, Amaki Takumi, Okayama Akihiro, Babitzke Paul, Suzuki Kazushi, Romeo Tony

Abstract excerpt

The widely conserved protein CsrA (carbon storage regulator A) globally regulates bacterial gene expression at the post-transcriptional level. In many species, CsrA activity is governed by untranslated sRNAs, CsrB and CsrC in Escherichia coli, which bind to multiple CsrA dimers, sequestering them from lower affinity mRNA targets. Both the synthesis and turnover of CsrB/C are regulated. Their turnover requires the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to RNA, Bacterial

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Share to Terminator Regions, Genetic

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Identifiers

PMID: 27235416
DOI: 10.1093/nar/gkw484
PMCID: PMC5027483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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