Article
Comprehensive alanine-scanning mutagenesis of Escherichia coli CsrA defines two subdomains of critical functional importance.
The Journal of biological chemistry - 20 Oct 2006
Mercante Jeffrey, Suzuki Kazushi, Cheng Xiaodong, Babitzke Paul, Romeo Tony
Abstract excerpt
The RNA-binding protein CsrA (carbon storage regulator) of Escherichia coli is a global regulator of gene expression and is representative of the CsrA/RsmA family of bacterial proteins. These proteins act by regulating mRNA translation and stability and are antagonized by binding to small noncoding RNAs. Although the RNA target sequence and structure for CsrA binding have been well defined, little information...
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