Article
Regulatory circuitry of the CsrA/CsrB and BarA/UvrY systems of Escherichia coli.
Journal of bacteriology - 1 Sept 2002
Suzuki Kazushi, Wang Xin, Weilbacher Thomas, Pernestig Anna-Karin, Melefors Ojar, Georgellis Dimitris, Babitzke Paul, Romeo Tony
Abstract excerpt
The global regulator CsrA (carbon storage regulator) is an RNA binding protein that coordinates central carbon metabolism, activates flagellum biosynthesis and motility, and represses biofilm formation in Escherichia coli. CsrA activity is antagonized by the untranslated RNA CsrB, to which it binds and forms a globular ribonucleoprotein complex. CsrA indirectly activates csrB transcription, in an apparent...
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