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Article

RNA Polymerase II Trigger Loop Mobility: INDIRECT EFFECTS OF Rpb9.

The Journal of biological chemistry - 8 Jul 2016

Kaster Benjamin C, Knippa Kevin C, Kaplan Craig D, Peterson David O

Abstract excerpt

Rpb9 is a conserved RNA polymerase II (pol II) subunit, the absence of which confers alterations to pol II enzymatic properties and transcription fidelity. It has been suggested previously that Rpb9 affects mobility of the trigger loop (TL), a structural element of Rpb1 that moves in and out of the active site with each elongation cycle. However, a biochemical mechanism for this effect has not been defined. We...

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PMID: 27226557
DOI: 10.1074/jbc.M116.714394
PMCID: PMC4938204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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