Article
Heritability in inflammatory bowel disease: from the first twin study to genome-wide association studies.
Inflammatory bowel diseases - 1 Jun 2015
Gordon Hannah, Trier Moller Frederik, Andersen Vibeke, Harbord Marcus
Abstract excerpt
Since Tysk et al's pioneering analysis of the Swedish twin registry, twin and family studies continue to support a strong genetic basis of the inflammatory bowel diseases. The coefficient of heritability for siblings of inflammatory bowel disease probands is 25 to 42 for Crohn's disease and 4 to...
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