Combination Testing Using a Single MSH5 Variant alongside HLA Haplotypes Improves the Sensitivity of Predicting Coeliac Disease Risk in the Polish Population.

doi:10.1371/journal.pone.0139197

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Article

Combination Testing Using a Single MSH5 Variant alongside HLA Haplotypes Improves the Sensitivity of Predicting Coeliac Disease Risk in the Polish Population.

PloS one - 1 Jan 2015

Paziewska Agnieszka, Cukrowska Bozena, Dabrowska Michalina, Goryca Krzysztof, Piatkowska Magdalena, Kluska Anna, Mikula Michal, Karczmarski Jakub, Oralewska Beata, Rybak Anna, Socha Jerzy, Balabas Aneta, Zeber-Lubecka Natalia, Ambrozkiewicz Filip, Konopka Ewa, Trojanowska Ilona, Zagroba Malgorzata, Szperl Malgorzata, Ostrowski Jerzy

Abstract excerpt

Assessment of non-HLA variants alongside standard HLA testing was previously shown to improve the identification of potential coeliac disease (CD) patients. We intended to identify new genetic variants associated with CD in the Polish population that would improve CD risk prediction when used alongside HLA haplotype analysis. DNA samples of 336 CD and 264 unrelated healthy controls were used to create DNA pools...

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PMID: 26406233
DOI: 10.1371/journal.pone.0139197
PMCID: PMC4583383

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MSH5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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