Selected single-nucleotide polymorphisms in FOXE1, SERPINA5, FTO, EVPL, TICAM1 and SCARB1 are associated with papillary and follicular thyroid cancer risk: replication study in a German population.

doi:10.1093/carcin/bgw047

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Article

Selected single-nucleotide polymorphisms in FOXE1, SERPINA5, FTO, EVPL, TICAM1 and SCARB1 are associated with papillary and follicular thyroid cancer risk: replication study in a German population.

Carcinogenesis - 1 Jul 2016

Sigurdson Alice J, Brenner Alina V, Roach James A, Goudeva Lilia, Müller Jörg A, Nerlich Kai, Reiners Christoph, Schwab Robert, Pfeiffer Liliane, Waldenberger Melanie, Braganza Melissa, Xu Li, Sturgis Erich M, Yeager Meredith, Chanock Stephen J, Pfeiffer Ruth M, Abend Michael, Port Matthias

Abstract excerpt

Several single-nucleotide polymorphisms (SNPs) have been associated with papillary and follicular thyroid cancer (PTC and FTC, respectively) risk, but few have replicated. After analyzing 17525 tag SNPs in 1129 candidate genes, we found associations with PTC risk in SERPINA5, FTO, HEMGN (near FOXE1) and other genes. Here, we report results from a replication effort in a large independent PTC/FTC case-control...

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Identifiers

PMID: 27207655
DOI: 10.1093/carcin/bgw047
PMCID: PMC4936384

Genes

FOXE1
FTO
SERPINA5
TICAM1
EVPL
HEMGN
SCARB1
HSPA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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