Article
Genome-wide meta-analysis reveals novel susceptibility loci for thyrotoxic periodic paralysis.
European journal of endocrinology - 1 Dec 2020
Hoi-Yee Li Gloria, Cheung Ching-Lung, Zhao Shuang-Xia, Song Huai-Dong, Wai-Chee Kung Annie
Abstract excerpt
OBJECTIVE: Thyrotoxic periodic paralysis (TPP) is a rare and potentially fatal complication of hyperthyroidism. By meta-analysis of genome-wide association studies, we aim to discover novel susceptibility loci and understand the pathogenesis of TPP. METHODS: This meta-analysis comprised 319 TPP cases and 3516 healthy controls from three independent cohorts (two from Hong Kong; one from Shanghai). Genetic variants...
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