Article
Whole exome and target sequencing identifies MAP2K5 as novel susceptibility gene for familial non-medullary thyroid carcinoma.
International journal of cancer - 15 Mar 2019
Ye Feng, Gao Hongwei, Xiao Lin, Zuo Zhixiang, Liu Yueping, Zhao Qi, Chen Huijiao, Feng Weiyi, Fu Bo, Sun Linyong, Jiang Xiaolin, He Du, Jiang He, Yang Mei, Li Li, Chen Fei, Liu Xiang, Li Shuang, Li Zhihui, Jiang Yong, Cheng Liang, Bu Hong
Abstract excerpt
Although the genotype-phenotype for familial medullary thyroid carcinoma (FMTC) is well studied, only few low susceptibility risk loci were identified for familial non-medullary thyroid carcinoma (FNMTC). The aim of this study is to screen and identify high-penetrate genes for FNMTC. A total of 34 families with more than two first-degree relatives diagnosed as papillary thyroid cancer without other familial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.