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Article

Associations of mitochondrial polymorphisms with sporadic colorectal adenoma.

Molecular carcinogenesis - 1 May 2018

Thyagarajan Bharat, Guan Weihua, Fedirko Veronika, Barcelo Helene, Ramasubramaian Ramya, Gross Myron, Goodman Michael, Bostick Roberd M

Abstract excerpt

Somatic mutations in mitochondrial DNA have been reported in colorectal adenomatous polyps (adenomas), the precursors to most colorectal cancers. However, there are no reports of associations of germline variation in mitochondrial DNA with adenoma risk. We investigated associations of germline polymorphisms in the displacement loop (D-loop) and non-D-loop region of the mitochondrial genome with incident, sporadic...

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Identifiers

PMID: 29323753
DOI: 10.1002/mc.22783
PMCID: PMC5880705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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