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Article

High rate of mutation in mitochondrial DNA displacement loop region in human colorectal cancer.

Diseases of the colon and rectum - 1 Mar 2009

Akouchekian Mansoureh, Houshmand Massoud, Hemati Simin, Ansaripour Mohammad, Shafa Mehdi

Abstract excerpt

PURPOSE: Mitochondrial DNA mutations are found in many kinds of human cancer and the 1.1 kb displacement loop region has been identified as a "hot spot" for mutation in mitochondrial DNA of tumors. This study evaluated the mutation frequencies in hypervariable regions of mitochondrial displacement loop in patients with colorectal cancer. METHODS: We examined the frequency of mutations in the mitochondrial DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19333057
DOI: 10.1007/DCR.0b013e31819acb99

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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