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Article

Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk.

British journal of cancer - 16 Dec 2008

Webb E, Broderick P, Chandler I, Lubbe S, Penegar S, Tomlinson I P M, Houlston R S

Abstract excerpt

Several lines of evidence implicate mitochondrial dysfunction in the development of cancer. To test the hypothesis that common mtDNA variation influences the risk of colorectal cancer (CRC), we genotyped 132 tagging mtDNA variants in a sample of 2854 CRC cases and 2822 controls. The variants exam...

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Identifiers

PMID: 19050702
DOI: 10.1038/sj.bjc.6604805
PMCID: PMC2607223

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19050702-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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