Article
HIV-1 Genetic Variation Resulting in the Development of New Quasispecies Continues to Be Encountered in the Peripheral Blood of Well-Suppressed Patients.
PloS one - 1 Jan 2016
Dampier Will, Nonnemacher Michael R, Mell Joshua, Earl Joshua, Ehrlich Garth D, Pirrone Vanessa, Aiamkitsumrit Benjamas, Zhong Wen, Kercher Katherine, Passic Shendra, Williams Jean W, Jacobson Jeffrey M, Wigdahl Brian
Abstract excerpt
As a result of antiretroviral therapeutic strategies, human immunodeficiency virus type 1 (HIV-1) infection has become a long-term clinically manageable chronic disease for many infected individuals. However, despite this progress in therapeutic control, including undetectable viral loads and CD4+ T-cell counts in the normal range, viral mutations continue to accumulate in the peripheral blood compartment over...
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