Genotypic Resistance Testing of HIV-1 DNA in Peripheral Blood Mononuclear Cells

doi:10.1128/cmr.00052-22

Article

Genotypic Resistance Testing of HIV-1 DNA in Peripheral Blood Mononuclear Cells

14 Sept 2022

Abstract excerpt

HIV-1 DNA exists in nonintegrated linear and circular episomal forms and as integrated proviruses. In patients with plasma viremia, most peripheral blood mononuclear cell (PBMC) HIV-1 DNA consists of recently produced nonintegrated virus DNA while in patients with prolonged virological suppression (VS) on antiretroviral therapy (ART), most PBMC HIV-1 DNA consists of proviral DNA produced months to years earlier....

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.