Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV evolution and diversity in ART-treated patients.

Retrovirology - 30 Jan 2018

van Zyl Gert, Bale Michael J, Kearney Mary F

Abstract excerpt

Characterizing HIV genetic diversity and evolution during antiretroviral therapy (ART) provides insights into the mechanisms that maintain the viral reservoir during ART. This review describes common methods used to obtain and analyze intra-patient HIV sequence data, the accumulation of diversity prior to ART and how it is affected by suppressive ART, the debate on viral replication and evolution in the presence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Retroviral Agents
Share to Antiretroviral Therapy, Highly Active
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HIV Infections

Share to Proviruses

Share to Viral Load

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 29378595
DOI: 10.1186/s12977-018-0395-4
PMCID: PMC5789667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV evolution and diversity in ART-treated patients.PMID 29378595Read ↗

HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy.Semantic proximity Read ↗

HIV-1 genetic diversity and divergence and its correlation with disease progression among antiretroviral naïve recently infected individuals.Semantic proximity Read ↗

HIV sequence diversity during the early phase of infection is associated with HIV DNA reductions during antiretroviral therapy.Semantic proximity Read ↗

HIV populations are large and accumulate high genetic diversity in a nonlinear fashion.Semantic proximity Read ↗

An increasing proportion of monotypic HIV-1 DNA sequences during antiretroviral treatment suggests proliferation of HIV-infected cells.Semantic proximity Read ↗

HIV Rebound Is Predominantly Fueled by Genetically Identical Viral Expansions from Diverse ReservoirsSemantic proximity Read ↗

Why the HIV Reservoir Never Runs Dry: Clonal Expansion and the Characteristics of HIV-Infected Cells Challenge Strategies to Cure and Control HIV InfectionSemantic proximity Read ↗

Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruptionSemantic proximity Read ↗

The origin and diversity of the HIV-1 pandemic.Semantic proximity Read ↗

HIV Proviral Burden, Genetic Diversity, and Dynamics in Viremic Controllers Who Subsequently Initiated Suppressive Antiretroviral Therapy.Semantic proximity Read ↗

HIV reservoirs are dominated by genetically younger and clonally enriched provirusesSemantic proximity Read ↗

Challenges for accurate HIV diagnosis: viral genetic diversity and acute infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.