Article
A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.
Annals of the rheumatic diseases - 1 Jan 2017
Márquez Ana, Vidal-Bralo Laura, Rodríguez-Rodríguez Luis, González-Gay Miguel A, Balsa Alejandro, González-Álvaro Isidoro, Carreira Patricia, Ortego-Centeno Norberto, Ayala-Gutiérrez María M, García-Hernández Francisco José, González-Escribano M Francisca, Sabio José Mario, Tolosa Carles, Suárez Ana, González Antonio, Padyukov Leonid, Worthington Jane, Vyse Timothy, Alarcón-Riquelme Marta E, Martín Javier
Abstract excerpt
OBJECTIVES: During the last years, genome-wide association studies (GWASs) have identified a number of common genetic risk factors for rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). However, the genetic overlap between these two immune-mediated diseases has not been thoroughly examined so far. The aim of the present study was to identify additional risk loci shared between RA and SLE. METHODS:...
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