Article
Prediction of New Risk Genes and Potential Drugs for Rheumatoid Arthritis from Multiomics Data.
Computational and mathematical methods in medicine - 1 Jan 2022
Birga Anteneh M, Ren Liping, Luo Huaichao, Zhang Yang, Huang Jian
Abstract excerpt
Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease for which there is a lack of therapeutic options. Genome-wide association studies (GWASs) have identified over 100 genetic loci associated with RA susceptibility; however, the most causal risk genes (RGs) associated with, and molecular mechanism underlying, RA remain unknown. In this study, we collected 95 RA-associated loci from multiple GWASs...
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