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Article

Common and different genetic background for rheumatoid arthritis and coeliac disease.

Human molecular genetics - 1 Nov 2009

Coenen Marieke J H, Trynka Gosia, Heskamp Sandra, Franke Barbara, van Diemen Cleo C, Smolonska Joanna, van Leeuwen Miek, Brouwer Elisabeth, Boezen Marike H, Postma Dirkje S, Platteel Mathieu, Zanen Pieter, Lammers Jan-Willem W J, Groen Harry J M, Mali Willem P T M, Mulder Chris J, Tack Greetje J, Verbeek Wieke H M, Wolters Victorien M, Houwen Roderick H J, Mearin M Luisa, van Heel David A, Radstake Timothy R D J, van Riel Piet L C M, Wijmenga Cisca, Barrera Pilar, Zhernakova Alexandra

Abstract excerpt

Recent genome-wide association studies (GWAS) have revealed genetic risk factors in autoimmune and inflammatory disorders. Several of the associated genes and underlying pathways are shared by various autoimmune diseases. Rheumatoid arthritis (RA) and coeliac disease (CD) are two autoimmune disorders which have commonalities in their pathogenesis. We aimed to replicate known RA loci in a Dutch RA population, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19648290
DOI: 10.1093/hmg/ddp365

Genes

LPP
MMEL1
PFKFB3
PRKCQ
PTPN22
TNFAIP3
TNFRSF14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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