Article
Identification of a mutation causing a defective spindle assembly checkpoint in high ethyl caproate-producing sake yeast strain K1801.
Bioscience, biotechnology, and biochemistry - 1 Aug 2016
Goshima Tetsuya, Nakamura Ryo, Kume Kazunori, Okada Hiroki, Ichikawa Eri, Tamura Hiroyasu, Hasuda Hirokazu, Inahashi Masaaki, Okazaki Naoto, Akao Takeshi, Shimoi Hitoshi, Mizunuma Masaki, Ohya Yoshikazu, Hirata Dai
Abstract excerpt
In high-quality sake brewing, the cerulenin-resistant sake yeast K1801 with high ethyl caproate-producing ability has been used widely; however, K1801 has a defective spindle assembly checkpoint (SAC). To identify the mutation causing this defect, we first searched for sake yeasts with a SAC-defect like K1801 and found that K13 had such a defect. Then, we searched for a common SNP in only K1801 and K13 by...
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