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Article

Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes.

The Journal of pharmacology and experimental therapeutics - 1 Jul 2016

Zhang Hai-Feng, Wang Huan-Huan, Gao Na, Wei Jun-Ying, Tian Xin, Zhao Yan, Fang Yan, Zhou Jun, Wen Qiang, Gao Jie, Zhang Yang-Jun, Qian Xiao-Hong, Qiao Hai-Ling

Abstract excerpt

Due to a lack of physiologic cytochrome P450 (P450) isoform content, P450 activity is typically only determined at the microsomal level (per milligram of microsomal protein) and not at the isoform level (per picomole of P450 isoform), which could result in the misunderstanding of variations in P450 activity between individuals and further hinder development of personalized medicine. We found that there were large...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27189963
DOI: 10.1124/jpet.116.233635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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