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Article

Cytochromes p450: roles in diseases.

The Journal of biological chemistry - 14 Jun 2013

Pikuleva Irina A, Waterman Michael R

Abstract excerpt

The cytochrome P450 superfamily consists of a large number of heme-containing monooxygenases. Many human P450s metabolize drugs used to treat human diseases. Others are necessary for synthesis of endogenous compounds essential for human physiology. In some instances, alterations in specific P450s affect the biological processes that they mediate and lead to a disease. In this minireview, we describe medically...

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Identifiers

PMID: 23632021
DOI: 10.1074/jbc.R112.431916
PMCID: PMC3682515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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