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Article

Nuclease Footprints in Sperm Project Past and Future Chromatin Regulatory Events.

Scientific reports - 17 May 2016

Johnson Graham D, Jodar Meritxell, Pique-Regi Roger, Krawetz Stephen A

Abstract excerpt

Nuclear remodeling to a condensed state is a hallmark of spermatogenesis. This is achieved by replacement of histones with protamines. Regions retaining nucleosomes may be of functional significance. To determine their potential roles, sperm from wild type and transgenic mice harboring a single copy insert of the human protamine cluster were subjected to Micrococcal Nuclease-seq. CENTIPEDE, a hierarchical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27184706
DOI: 10.1038/srep25864
PMCID: PMC4869110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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