Article
Family-assisted inference of the genetic architecture of major histocompatibility complex variation.
Molecular ecology resources - 1 Nov 2016
Gaigher A, Burri R, Gharib W H, Taberlet P, Roulin A, Fumagalli L
Abstract excerpt
With their direct link to individual fitness, genes of the major histocompatibility complex (MHC) are a popular system to study the evolution of adaptive genetic diversity. However, owing to the highly dynamic evolution of the MHC region, the isolation, characterization and genotyping of MHC genes remain a major challenge. While high-throughput sequencing technologies now provide unprecedented resolution of the...
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