PyMSQ: a Python package for fast Mendelian sampling (co)variance and haplotype-based similarity in genomic selection.

Abstract excerpt

BACKGROUND: While genomic selection boosts rapid genetic gains by leveraging dense marker data for genomic estimated breeding values (GEBVs), prolonged application can reduce haplotype diversity and increase inbreeding. To address these risks, recent studies indicate that selecting on Mendelian sampling variance (MSV) and covariance (MSC) can partly mitigate the loss of genetic variation by exploiting...

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