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Article

Using bioinformatics to investigate functional diversity: a case study of MHC diversity in koalas.

Immunogenetics - 1 Dec 2024

Silver Luke W, McLennan Elspeth A, Beaman Julian, da Silva Karen Burke, Timms Peter, Hogg Carolyn J, Belov Katherine

Abstract excerpt

Conservation genomics can greatly improve conservation outcomes of threatened populations, including those impacted by disease. Understanding diversity within immune gene families, including the major histocompatibility complex (MHC) and toll-like receptors (TLR), is important due to the role they play in disease resilience and susceptibility. With recent advancements in sequencing technologies and bioinformatic...

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Computational Biology
Genetic Variation
Major Histocompatibility Complex
Toll-Like Receptors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39367971
DOI: 10.1007/s00251-024-01356-6
PMCID: PMC11496358

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