Article
A pan-cetacean MHC amplicon sequencing panel developed and evaluated in combination with genome assemblies.
Molecular ecology resources - 1 Jul 2024
Heimeier Dorothea, Garland Ellen C, Eichenberger Franca, Garrigue Claire, Vella Adriana, Baker C Scott, Carroll Emma L
Abstract excerpt
The major histocompatibility complex (MHC) is a highly polymorphic gene family that is crucial in immunity, and its diversity can be effectively used as a fitness marker for populations. Despite this, MHC remains poorly characterised in non-model species (e.g., cetaceans: whales, dolphins and porpoises) as high gene copy number variation, especially in the fast-evolving class I region, makes analyses of genomic...
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