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Article

Local Ancestry Inference in a Large US-Based Hispanic/Latino Study: Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

G3 (Bethesda, Md.) - 1 Jun 2016

Browning Sharon R, Grinde Kelsey, Plantinga Anna, Gogarten Stephanie M, Stilp Adrienne M, Kaplan Robert C, Avilés-Santa M Larissa, Browning Brian L, Laurie Cathy C

Abstract excerpt

We estimated local ancestry on the autosomes and X chromosome in a large US-based study of 12,793 Hispanic/Latino individuals using the RFMix method, and we compared different reference panels and approaches to local ancestry estimation on the X chromosome by means of Mendelian inconsistency rates as a proxy for accuracy. We developed a novel and straightforward approach to performing ancestry-specific PCA after...

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Identifiers

PMID: 27172203
DOI: 10.1534/g3.116.028779
PMCID: PMC4889649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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