Estimates of European Ancestry in U.S. Hispanics Using HFE p.C282Y (c.845G>A; rs1800562), a Highly Informative Autosomal Marker.

doi:10.1177/19450265261464225

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Estimates of European Ancestry in U.S. Hispanics Using HFE p.C282Y (c.845G>A; rs1800562), a Highly Informative Autosomal Marker.

Genetic testing and molecular biomarkers - 1 Jul 2026

Barton James C, Barton J Clayborn, Acton Ronald T

Abstract excerpt

BACKGROUND: We estimated European ancestry in U.S. Hispanics using HFE p.C282Y (c.845G > A; rs1800562), a highly informative autosomal marker of European ancestry. METHODS: We tabulated published p.C282Y allele frequencies in U.S. Hispanic control/population region/city cohorts. We assumed that Hispanics inherited p.C282Y from European ancestors only. We defined European ancestry (M) of each cohort as the...

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PMID: 42376730
DOI: 10.1177/19450265261464225

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