Article
Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits.
PloS one - 1 Jan 2017
Sofer Tamar, Baier Leslie J, Browning Sharon R, Thornton Timothy A, Talavera Gregory A, Wassertheil-Smoller Sylvia, Daviglus Martha L, Hanson Robert, Kobes Sayuko, Cooper Richard S, Cai Jianwen, Levy Daniel, Reiner Alex P, Franceschini Nora
Abstract excerpt
Admixture mapping can be used to detect genetic association regions in admixed populations, such as Hispanics/Latinos, by estimating associations between local ancestry allele counts and the trait of interest. We performed admixture mapping of the blood pressure traits systolic and diastolic blood pressure (SBP, DBP), mean arterial pressure (MAP), and pulse pressure (PP), in a dataset of 12,116 participants from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
